A dentist holding a Colgate toothpaste tube and toothbrush, speaking directly to the camera.

The ad opens with a dentist, wearing a white coat and red shirt, holding a tube of Colgate Total toothpaste and a toothbrush, speaking to a patient. The scene transitions to close-ups of the toothpaste tube and animated graphics showing spheres with colorful particles, representing bacteria. The graphics then show these bacteria accumulating on teeth. The ad concludes with a shot of the toothpaste tube against a white background with colorful wavy lines, and text overlay.