The question "You wear underwear?" is unexpected and humorous.

The ad opens with a man in a suit sitting in a restaurant with a city view, talking to another person off-screen. He asks if the other person wears underwear, then elaborates on the importance of quality fabrics. The scene cuts to a different man in a suit, who responds to the questions. The first man then explains that he wears modal fabric, or man-made underwear, because it's a 'prescription' to avoid chafing. The ad ends with a graphic displaying the brand name and website.